"No one ever claimed they were unblinded."
<AVII77 raising hand>
I believe they were unblinded.
I believe they were unblinded to the fact that PFS was futile and likely unblinded to the fact that OS was futile. They may have been unblinded to the knowledge that PFS and OS were numerically WORSE for DCVax.
They are playing a game of semantics by saying they were blinded. They were likely blinded to the fact that patient A received Dcvax and patient B received placebo.
But thats not the blinding I'm talking about. And thats not the blinding that counts when making a subsequent change to efficacy measures.