And bizarrely all those posts stand, and my post in reply to Sentiment's political rant got deleted off topic by admin:
My post in reply to Sentiment's which follows mine below:
Post Date: 7/31/2020 11:02:22 AM in reply to 157285237 by sentiment_stocks
Board: NorthWest Biotherapeutics Inc. Reason: Off-Topic
It was put in the spotlight by dotard Trump so both sides have taken trials and studies further. As a result, there have been various and different findings, including its dangerous side effects previously undetected, of course there are also some "beautiful" things claimed by the dotard, who is everyday laughing stock all around the world, and one half of the America, excluding diehard republicans.
If history is of any use, it shows ideology and extreme religious belief are enemy of human beings.
To be a free man, one ought to be free of the both above, and be literate.
I share the feeling of Smokey that seeing so many political/ideological maniacs in this board makes me doubt my conviction in my investment.
But life is complex and that makes it worthy of living!
And her post I relied to:
sentiment_stocks Member Level Friday, 07/31/20 10:25:41 AM
Re: exwannabe post# 297690 0
Post # of 297898
There it is again... one of the worlds most dangerous drugs <that’s sarcasm, Longfellow>... chloroquine.
One of the world’s oldest drugs, and for decades previously thought to be quite safe, but now the worlds medical community has deemed it to be practically a killer.
Quote:But the anti-malarial drug, chloroquinone, is known to block autophagy and so the researchers added that into the mix and immediately the BRAF inhibiting drug started working again. By the end of 2016 a number of patients had been treated with this repurposed drug and all responded.
A 2014 review (2) of chloroquinone had found that it could suppress tumour growth and metastasis. Although it showed this action on cancer cells in vitro, researchers have shown in real life it can also act on the blood vessels of a tumour. With cisplatin, it did not work on cell cultures but did when used in vivo, greatly increasing the toxicity of the drug.
In 2017 research (3), University of Kentucky scientists Vivek Rangnekar and Ravshan Burikhanov showed that chloroquinone empowered normal cells with wild type p53, to express a protein Par-4, and stop metastasis in p53 deficient cancer cells (about 50% of cancer cells). Par-4 is essential for cell death and cancer cells switch it off.
As long ago as 2002, scientists from the Chase Cancer Center (4) argued that glutathione-S-transferase was what cancer cells used to block cancer drugs after a period of time but that drugs like chloroquinone could prevent that extending the life of many drugs in most cancers.
Chris Woollams, former Oxford University Biochemist and a founder of CANCERactive said, "The research is mounting along a number of avenues, and given that some affect brain cancer and melanoma for which existing treatments are poor, we will regularly follow chloroquine and produce updates. It is known to cause oxidative stress in Plasmodium, the malarial bug. It is exactly this oxidative stress that gives it anti-cancer properties too. It seems to help Temozolomide become more effective and work for longer. It reduces the state of hypoxia in brain cancer cells and clinical trials are taking place (5)."
Hmmm... No mention of any dangerous heart issues caused by chloroquine found in that article. Just chloroquine helping to prolong the lives of some brain cancer patients.