Re: Gene Therapy Is Nearing a Major Breakthrough
Interesting article. Does this virus vector permanently alter DNA in ALL cells including Ovaries and testes? If so, this would affect future generations if given to someone not past reproductive years. Most likely good, but hard to prove in a reasonable clinical trial time frame. Especially bad since there is no mechanism for reversal should an unanticipated negative effect occur in some people--e.g. modifies another protein peculiar to a small subset of population and therefore missed in clinical trials or happen to also hit a protein only active in early fetus development.