Karuna Therapeutics in dementia-related psychosis, and Axovant Gene therapy in PD | ACAD Message Board Posts

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Msg  17086 of 17156  at  9/23/2020 12:51:18 PM  by

Biotech_Jim


 In response to msg 17084 by  sphericalkutz
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Re: Karuna Therapeutics in dementia-related psychosis, and Axovant Gene therapy in PD

 I believe that I did mention that these companies are early. Simply I wanted to alert the board. But make no doubt, AXGT is a totally revamped and different company than the David Hung failed AXON. I stayed away from that company.
 
 Scientific question to those so inclined. I have my view on this, but can there be a signal in midbrain dopamine nerve terminals (caudate-putamen complex), by dopamine via reuptake by the dopamine transporter, that signals back to substantia nigra dopamine cell bodies, that can preserve these neurons from cell death that progressively occurs in PD?
 
 Think about it. Complex Q, to be sure. The answer has broad implications for this terrible disorder.


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Msg # Subject Author Recs Date Posted
17087 Re: Karuna Therapeutics in dementia-related psychosis, and Axovant Gene therapy in PD sphericalkutz 2 9/23/2020 3:26:19 PM
17091 Re: Karuna Therapeutics in dementia-related psychosis, and Axovant Gene therapy in PD BelieverTim 1 9/24/2020 2:50:20 PM






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