T-VEC + Permbrolizumab data in liver cancer | PVCT Message Board Posts

Provectus Biopharmaceuticals, Inc.

  PVCT website

PVCT   /  Message Board  /  Read Message

 

 






Keyword
Subject
Between
and
Rec'd By
Authored By
Minimum Recs
  
Previous Message  Next Message   Post Message   Post a Reply return to message boardtop of board
Msg  53651 of 54002  at  7/1/2020 7:41:56 PM  by

vorlon1966


 In response to msg 53650 by  canis_star
view thread

Re: T-VEC + Permbrolizumab data in liver cancer

Not surprising. Tvec causes apoptosis which doesnít really release cancer specific antigens for bystander effect.....no matter what they may claim. Itís not a good primer for the immune system. PV-10 causes autolysis first followed by quick attempt at apoptosis.....then autolysis to necrosis takes over faster than apoptosis. In solid tumor ablation by PV-10 injection you end up seeing byproducts of autolysis, autophagy, apoptosis, and necrosis. In realty PV-10 trips all these mechanisms resulting in cascade byproducts in all paths. Those researchers of PV-10 find the byproducts they are looking for. One researcher may say PV-10 causes apoptosis...and for a snapshot in time it does. But in reality, autolysis spills out acidic hydrolyses of the lysosomes. That starts cell death cascade. The cancer cell then kicks in apoptosis to try to self destruct without releasing antigens for normal cell death. However, autolysis continues and overcomes apoptosis path and results in necrosis which blows apart the micelle bilayer cell membrane releasing the cancer specific antigens in bits not tied to normal antigens. The immune system can now see bits of cancer specific antigens without being fooled by normal antigens telling the immune system the cell was normal.


     e-mail to a friend      printer-friendly     add to library      
| More
Recs: 7     Views: 243
Previous Message  Next Message   Post Message   Post a Reply return to message boardtop of board

Replies
Msg # Subject Author Recs Date Posted
53670 Re: T-VEC + Permbrolizumab data in liver cancer pacificnorthwest1 1 7/6/2020 11:49:21 PM






Financial Market Data provided by
.


Loading...