CTLA4 lesson and the need for IPI in PV-10 triple combo. | PVCT Message Board Posts

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Msg  50452 of 50585  at  8/14/2019 9:16:01 PM  by

vorlon1966

The following message was updated on 8/14/2019 9:17:28 PM.

 In response to msg 50451 by  vorlon1966
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Re: CTLA4 lesson and the need for IPI in PV-10 triple combo.

More wisdom: add IPI in lower dose...just enough to allow the APC’s to get their cancer cell specific antigen presentation done to start the cascade and kick start CD+T killer Tcell cloning and IFN gamma production ...leading to Bcell antibody production ...but not too much to interfere with long term regulation needed to prevent autoimmune disease. Just enough to delay the Treg response.


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Msg # Subject Author Recs Date Posted
50453 Re: CTLA4 lesson and the need for IPI in PV-10 triple combo. ---CpG pacificnorthwest1 0 8/14/2019 10:00:29 PM


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