The Wilton Approach - Splice Switching Oligos (conclusively corrected) | SRPT Message Board Posts

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Msg  14207 of 14237  at  6/23/2020 10:55:09 PM  by

schmiggins


 In response to msg 14189 by  schmiggins
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Re: The Wilton Approach - Splice Switching Oligos (conclusively corrected)

Out yesterday....something on "how it works" (posted today on srpt twitter page):

https://pubmed.ncbi.nlm.nih.gov/32555469/

I see I wasn't the only one wondering, but looks like they are getting closer - to determining why (naturally) one path is taken more than another ... or in some cases always or never etc etc...an ongoing exploration.

Wilton's tech forces the alternative path to be taken, a path that's never taken naturally ... but apparently is in there somewhere and CAN be taken..


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