This has been a great investment. I think there remains significant upside potential over the intermediate to long-term. Still, it has gone up a lot in a short time. I personally do not expect significant price appreciation until we get closer to the November AHA meeting. In fact, I would not be at all surprised to see some retracement. Still, I am not selling my shares. In my opinion, there is real promise in their technology and their targets.
I also agree, that the ARWR timeline, in the context of the timelines, strengths and weaknesses of its competitors' technologies, must be closely examined. That is essentially what I spend much of my time doing.