KYMRIAH and Yescarta
YMRIAH and Yescarta are not your typical "pills"/drugs. It takes 17 days to administer Yescarta with trained technicians and doctors - thus the high cost.
KYMRIAH has had serious manufacturing issues - so much so that the FDA won't let it sell commercially (and make money) - but can currently only be given its CAR T free.
But, the drugs work.. And, Yescarta has the better C/R. etc. - and is the leading commercial seller.
Most patients that need Yescarta or Kymriah and don't get it, will be dead within 1 year.
I don't expect any Yescarta like FDA approved drugs in 2019 - except from the ZUMA pipeline.