Savara Announces Results of IMPALA, a Phase 3 Study of Molgradex for the Treatment of Autoimmune Al | INSM Message Board Posts

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Msg  46233 of 46388  at  6/12/2019 9:33:42 PM  by

b_leaguered


 In response to msg 46228 by  tippy1
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Re: Savara Announces Results of IMPALA, a Phase 3 Study of Molgradex for the Treatment of Autoimmune Alveolar Pulmonary Proteinosis (aPAP)

I was concerned when you first posted that SVRA potentially had a product that could compete with Arikayce in treatment of NTM. Since then, we've learned a lot. Molgradex can only enhance macrophage activity, it can't rid macrophages of an existing NTM infection. The CEO, Rob Neville, who sat in on the recent FDA session on NTM treatment, has said so much himself, in that he believes that Molgradex may be an adjunct, not a cure. With Arikayce, we have a cure. I cannot believe all the people on the FDA panel who question eradication of the NTM organism as a good end point. What are they thinking? We're talking about a specific disease caused by a specific organism, are we not? If you get rid of it, well, there may be other health issues that could cloud the benefit. Can we at least admit that eradication of this specific pathogen is a step forward? Apparently not, because Arikayce has not provided them full health. What therapy can provide full health?


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Msg # Subject Author Recs Date Posted
46236 Re: Savara Announces Results of IMPALA, a Phase 3 Study of Molgradex for the Treatment of Autoimmune Alveolar Pulmonary Proteinosis (aPAP) bohemian 0 6/13/2019 8:37:54 AM


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