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Msg  166925 of 167953  at  8/9/2022 5:56:49 PM  by

rynotheknife


 In response to msg 166914 by  ZFP
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Re: Pipeline leverage

"18 of 23 programs in Sangamo pipeline"... I'm always wrong, but SGMO's website shows only 18 programs in the pipeline... but so what, why not pencil in a few more boxes for Base Editing and include those in the pipeline, too

which begs the question, "what constitutes a 'program' to be included in a 'pipeline'?"

none of SGMO's 14 preclinical pipeline programs have even filed an IND yet... that sounds like developmental programs not pipeline programs... the 4 programs re KITE, ALS, and Huntington's have been dead-in-the water for quite some time, there's been nothing but radio silence on the 7 CNS programs, and the 3 CAR-Tregs programs seem to be awaiting proof-of-concept from TX200

and there's 4 programs in the clinic... I think both Hemo A and SCD are dead-men-walking, Fabry is a long way from a BLA and has a very limited market potential, and TX200 is all about safety & tolerability while hoping to get POC sometime in 2023

but those 18 pipeline boxes certainly look impressive for the uninitiated :-)


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Replies
Msg # Subject Author Recs Date Posted
166927 Re: Pipeline leverage ZFP 0 8/9/2022 7:20:54 PM




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