Heard about this just today... making it sound like it's the best thing since slice bread / DNA:
The wonder SGMO / Zinc fingers seem like old news. All the hype is around Crispr
"The technology, called prime editing, has been described as a "genetic word processor" able to accurately re-write the genetic code. It has been used to correct damaging mutations in the lab, including those that cause sickle cell anaemia."
Prime editing: DNA tool could correct 89% of genetic defects
By James Gallagher Health and science correspondent. *
* 1. LINK TO Article
Much of the excitement has centred on a technology called Crispr-Cas9, which was developed just seven years ago.
It scans DNA for the right spot and then, like a microscopic pair of scissors, cuts it in two.
This creates the opportunity to edit the DNA.
the edits are not always perfect and the cuts can end up in the wrong
place. Both issues are a problem for using the technology in medicine.
The promise of prime editing is precision...."