Protein Vaccines have better and longer immune response in children vs mRNA - Henry, Red, Muddy?? | NVAX Message Board Posts


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Msg  125401 of 134077  at  5/3/2021 8:15:20 PM  by

Stock Warrior

The following message was updated on 5/3/2021 8:50:59 PM.

 In response to msg 125108 by  sbiller1
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Re: Protein Vaccines have better and longer immune response in children vs mRNA - Henry, Red, Muddy??

Thanks much, Henry for your expert insights here. Wondering what Red & Muddy have to think about this new published data?

In case you missed it, here's Henry's response to sbiller's post:

Wow, look what I missed today!

"I can only beg to ask what was Joe Biden talking about last week when he mentioned "Novavax."

Anyway, from this earlier post we have worked with 3M-052-SE adjuvant. It has emerged as one of the best for our antigens.

I'm surprised that 15 ug of the soluble version of the spike protein did so well so yes,
it's the adjuvant.

This soluble version is missing the heptad repeat, transmembrane domain and cytoplasmic tail.

Using the secreted protein expression methodology seen here we know expression levels are pretty low in these cells."

Link to the study & sbiller's post. (Thanks again, sbiller):

https://www.biorxiv.org/content/10.1101/2021.04.05.438479v1

https://www.investorvillage.com/smbd.asp?mb=193&mn=125108&pt=msg&mid=21963141


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