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Msg  237 of 246  at  1/23/2021 10:02:01 PM  by

zanispetros


South Africa variant


The below paper showed that only convalescent sera with neutralizing Ab titre around 2000 or higher have some effect on the variant 501Y.V2 from South Africa.

https://www.biorxiv.org/content/10.1101/2021.01.18.427166v1

Testing will have to be done to see if Ab titre from vaccine-treated patients correlates with convalescent sera in terms of protecting against a particular variant like 501Y.V2. However, it seems reasonable that a vaccine with higher titre would give better chance of protection.

The Novavax vaccine has been shown to generate neutralizing Ab titre at 3906 after the second shot. The next highest is the Moderna vaccine at 1179. So, at least for now, it looks like the Novavax vaccine gives the best chance of protection against the 501Y.V2 variant.
 


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Msg # Subject Author Recs Date Posted
238 Re: South Africa variant sooner_or_later55 1 1/24/2021 8:20:14 AM




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