Portola Pharmaceuticals Presents New In Vitro Data | PTLA Message Board Posts

Portola Pharmaceuticals, Inc.

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Msg  6379 of 6590  at  7/16/2019 12:19:35 AM  by

tjinvest


 In response to msg 6377 by  JoeFlow
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Re: Portola Pharmaceuticals Presents New In Vitro Data

Upon further research, maybe neither issue is a concern.  Reading the package insert was informative.
https://www.drugs.com/dosage/andexxa.html

(1) There is no mention of blood concentrations or testing.  The Andexxa dosing chart is based solely on which inhibitor drug&dose and *when* last taken.  If unknown, it assumes it was taken recently.

So they may just be getting patient drug & dose info and then quickly guestmating a high or low dose of Andexxa.

(2) Also, the complaint about Andexxa & reconsitution delay might be more procedural than anything to do with the drug.  It looks like a pharmacist could have some ready in 15 minutes.  It's a manual, slow process - especially for multiple vials.  I can't imagine pharmacists would be happy mixing this stuff up multiple times on a shift.  But it didn't look unworkable by any means. 



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