Portola Pharmaceuticals Presents New In Vitro Data | PTLA Message Board Posts

Portola Pharmaceuticals, Inc.

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Msg  6377 of 6389  at  7/10/2019 11:14:31 AM  by

JoeFlow


 In response to msg 6375 by  norseml
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Re: Portola Pharmaceuticals Presents New In Vitro Data

 According to the summary conclusions in the paper Ernie posted:
 
"This analysis underlines the usefulness of rapid DOAC measurement and the value of PopPK models to estimate concentrations at trough in a context where the post-intake delay is unmanageable." 
 
This struck me as being somewhat of a promotion of an assay in development.  This coupled with the need to "estimate concentrations at trough" implies a requirement to know when the patient last ingested their prescribed DOAC, followed by multiple plasma samplings to determine when the DOAC will be at minimum levels - meanwhile, the patient bleeds.
 
I agree with docoftheforce regarding the significance of the in-vitro data recently reported as being potentially practice-changing. 


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Replies
Msg # Subject Author Recs Date Posted
6379 Re: Portola Pharmaceuticals Presents New In Vitro Data tjinvest 5 7/16/2019 12:19:35 AM


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