AXS-05 shows positive results for major depression disorder | CNCE Message Board Posts

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Msg  1303 of 1397  at  1/7/2019 8:59:25 AM  by

OFP

The following message was updated on 1/7/2019 9:00:56 AM.

AXS-05 shows positive results for major depression disorder

 
Impressively significant results for treatment resistant MDD for Axsome's dextromethorphan/bupropion combo (similar strategy to ATP-786). Otsuka looked at '786 for depression (also for treatment resistant disease if I recall correctly) and decided to discontinue testing. AXSM seems to have found the right path/compound. Their active control was bupropion which only had an 18% response rate which is quite low so maybe something to pay attention to as a detraction from results but on it's face quite impressive.
 
 


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