HPV-16 leapfrogs | PGEN Message Board Posts


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Msg  53980 of 54572  at  6/1/2023 7:53:29 AM  by

Redwood1205


 In response to msg 53977 by  rubraquercus
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Re: HPV-16 leapfrogs

 Rub
I realize that every company but Precigen blows your socks off but this is clearly not a leap frog. 
Precigen 2009 had a 30% response rate when combined with the inferior MerckAG checkpoint on patients who had already failed Keytruda. Even if you only add 18% to 30% you get a better OR for 2009 if given first line with Keytruda.   
Interesting how they had little info on the 15 patients treated that had failed Keytruda initially. They must have started the trial with this cohort.
More than likely Precigen will be allowed to shift  their new 2009 trial to first line after treating a number of patients second line  and then  including the first line cohort  that cohort into a larger pinitol trial.  


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Msg # Subject Author Recs Date Posted
53981 Re: HPV-16 leapfrogs Redwood1205 0 6/1/2023 9:55:02 AM




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