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Re: i saved your post WST before you deleted it. Its better to be honest then to pretend. Havent longs on this board done that for a long enough time already?"Inherent in investing in highly speculative story stocks like Intrexon is that most will fail so unless you have a sell discipline that cuts down on your losses, the last thing you will worry about is beating the averages." I think you still take the cake for dumbest statements. If you are not worried about beating the market averages what are you doing investing in new emerging growth companies. Why would anyone invest in venture capital? "Not when that "any information" is incorrect and/or lacking a firm grip on reality" If you have no other information how do you know the information is incorrect. Even if it could be thrown out on logical grounds you still are no worse off than no information. "If you believe Venture Capitalists have no idea or understanding of a company that is going to pitch them , then you are a bigger idiot than even i thought." I am not saying they don't understand their industries. I am saying they don't understand what the company is trying to do or how they plan to do it. Why do you think they sign NDA's if the venture capitalist's already know everything. Don't you think that these startups need to have original ideas that the venture people aren't aware of. What is their advantage otherwise? If a person comes up with a brilliant knew idea, don't you have to listen to him/her "Tell the board what are the weaknesses of the Sleeping Beauty Platform as an example." I was making a general rhetorical point. Your question seems just a little naive. You don't provide an application or any context. Gasoline may be a great energy source for my car but I wouldn't drink it myself. I also would not apply SB technology to in vivo edits. You also don't refer to any particular version of SB. There are differences. You should ask ZIOP about this. Gene transfer rates and payload can be increased. You also need to consider what additional technologies might be matched up with SB that takes advantage of one of SB's strengths. This might minimize or make the weakness irrelevant in an application. For example because of the higher payload one may be able to use SB to edit not just the T-cells target but to enable membrane bound IL-15, making gene transfer rate irrelevant beyond a certain point. You may also be able to construct other capabilities that enhance its use versus other mechanisms. Mabel this is my last response to you unless of course you want to provide the board with your understanding of the weaknesses of SB. Otherwise I have to conclude that is a waste of everyone's time to reply to your posts. |
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Msg # | Subject | Author | Recs | Date Posted |
35754 | Re: i saved your post WST before you deleted it. Its better to be honest then to pretend. Havent longs on this board done that for a long enough time already? | Mabel | 0 | 9/23/2019 9:22:52 AM |