Is something wrong with this site or my computer? I can't post an original thread. "Post Message does not operate. I have ro reply to an existing thread to get it to post. Same as yesterday.
First amendment posted yesterday.
Phase 3 testing Keytruda + 4157 vs Keytruda + placebo in non-small cell lung cancer.
From profile: " The goal of this study is to evaluate V940 plus pembrolizumab versus placebo plus pembrolizumab for the adjuvant treatment of completely resected (R0) Stage II, IIIA, IIIB (with nodal involvement [N2]) non-small cell lung cancer (NSCLC). The primary hypothesis is that V940 plus pembrolizumab is superior to placebo plus pembrolizumab with respect to disease-free survival (DFS) as assessed by the investigator."
Not yet recruiting. Estimated start next month. Est. completion June, 2030 but I expect interim reports similar to the P2 melanoma trial.
Estimated participants: 868.
No study sites identified yet.
MRK is sponsor with MRNA as collaborator.
It seems to me they have a lot of confidence to start a P3 in lung cancer before 4157/Keytruda is approved for melanoma. Put another way, they must have a lot of confidence the melanoma treatment will be approved.
Naturally, the slow and lazy market has not noticed.