Looks like Kraig needs some offsetting publicity about the long and productive history of using ZFNs from SGMO to enhance the selective process for developing their silk worms. ZFNs have been proven to hit the intended target in any gene sequence with an extremely high rate of success, not just in a lab, but in clinical trials. Not so with CRSPR, whose track record includes a large percentage of missed targets. This could result in creating a whole population of silk worms with no gene enhancement, only a partial enhancement, or worse yet, with an unintended genetic enhancement that makes them prolific producers...but of something other than spider silk. As we know, it's a long and difficult road from the test tube to the cocoon.