Ah if only Dr Crooke could have been as perfect as you. What is it you've accomplished in your lifetime?
Yes Ionis has had growing pains as well as fits and starts, but Dr Crooke created a whole new way of making drugs that IMO is starting to revolutionize the industry starting with diseases like SMA, ALS, Huntington's and more. And when you are on the bleeding edge of technology, you are going to get cut sometimes. The real test is how you react and recover (or not) and unfortunately you can't always tell immediately how you did. I think their pipeline of LICA drugs and Neuro drugs speak for itself.
Honestly, I think it was time for Stan to move on and let Brett and the others run with company going forward. While Stan was brilliant in science, Wall St did not have confidence in his business acumen. IMO 2021 is not going to be anything like 2020 and it will just go up from here.