Re: of interest eha
In the one write up on your link it indicated highly active at a single dose 10 µg/kg
Fractionated dosing (5 µg/kg, qw x 2 or q3d x 2) generated 33% more long-term tumor-free survivors compared to single-dose (10 µg/kg), demonstrating tolerability and enhanced efficacy in multi-dose and fractionated regimens.
If this data can be realized in humans, I would think that more frequent low dose at higher frequency may be the future an not worry about MTD.
Dose could also be adjusted depending on age and strength of patient
Sooner