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Msg  34754 of 34789  at  1/10/2020 11:34:20 AM  by

The Rooster


AB-506 presentation

 The AB-506 capsid inhibitor discontinuation presentation is on the Arbutus website.  It does seem like it was working pretty good (more than 200-fold decreases in HBV RNA and DNA).  But in the small sample size, Arbutus seems to be suggesting that Asian subjects were suffering ALT increases (i.e., liver toxicity) that were not seen in Caucasian subjects.  They conclude they remain committed to developing a next generation capsid inhibitor which could be very frightening to some investors.


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Msg # Subject Author Recs Date Posted
34755 Re: AB-506 presentation spaddy 1 1/13/2020 9:21:23 PM






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