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Msg  21662 of 21678  at  3/13/2019 11:03:36 PM  by

JoeFlow


 In response to msg 21661 by  Pacific
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Re: TGFβ1

 interesting, thanks....
 
yeah, TGFb has been around a long time and only now being looked at as a therapeutic target for cancer.  My lab was down the hall from the guy that originally cloned and did the initial characterization of TGFb when I was at MSKCC - Joan Massague.  He was world-famous back then and we're talking mid-1990s.....  May be one of those things where so much is known about TGFb and it's involved in so many physiological responses - nobody thought there would a therapeutic window, or at least thought safety might be a liability.  we will see...


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