Inspired by fairvalueforyou's post, I dug deeper into asthma clinical trial literature and wrote a blog post about it. Please take a critical look if you are interested:
In short, fairvalueforyou and I expect positive results from AZD1419. Specifically, I expect 20-50% patients stay controlled and therapy free beyond 26 weeks after withdrawal in the active arm, while all placebo lose control within 8 weeks after withdrawal.
There is potentially a group of patients stay controlled the entire 39 week of follow up, which suggests a remission for moderate to severe asthma.