Roughly 1 million knee replacements are done in the U.S. each year. (Numbers vary a bit depending on which site you go to.) That is expected to grow to over 2 million per year by 2030. (All those weekend road warriors pounding the pavement in search of a runner's high or dropping some poundage are going to start paying the piper.)
Anyway, here is an article from two days ago about treating with aspirin. I would think this group doesn't fully overlap with people already on aspirin for heart reasons, so additional patient growth opportunity. If they are younger and have good results with Vazalore, one would think many would come back to it once their heart doctor recommends taking aspirin in their older years.