BioSig Tech. (BSGM) & Electrophysiology Sector - A good read if you can handle scientific lingo... - BioSig Tech. (BSGM) & Electrophysiology Sector - InvestorVillage
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Msg  1195 of 1296  at  6/30/2020 11:47:12 AM  by

2abetteryear


A good read if you can handle scientific lingo...

Take some time to read through this when you have time (link below).
 
Here is but one excerpt:
 
Both REM(desivir) and MMPD exhibit a potent antiviral effect on SARS-CoV-2 at concentrations of 2.5µM and 5µM after a 4 hour pre-treatment12. REM pre-treatment at a 5µM concentration provides a 2.1-log decrease in titer at 16 hours-post infection (p=0.001) and a 3.9-log decrease in titer at 24 hours post-infection (p<0.001). MMPD causes a similar antiviral effect as REM at the 5µM concentration, exhibiting a 2.1-log decrease in titer at 16 hours-post infection (p=0.001) and a 2.7-log decrease in titer at 24 hours post-infection (p<0.001). The effect of REM was dose-dependent, with the 2.5µM concentration of REM decreasing the titer by 1-log at 16 hours post-infection (p=0.103) and 1.5-log at 24 hours post-infection (p=0.002). However, MMPD antiviral effects appeared to be less dose-dependent, maintaining a 1.9-log decrease in titer at 16 hours post-infection (p=0.003) and a 2.5-log decrease in titer at 24 hours post-infection (p=0.001) at a concentration of 2.5µM (Figure 1). At sixteen hours post-infection 2.5µM REM does not have a statistically significant (p<0.05) difference between REM and untreated samples, whereas MMPD significantly reduced the infectious titer at this time point. When compared directly, MMPD causes a significantly greater reduction in SARS-CoV-2 infectious particles at both the 16-hour (p=0.022) and 24-hour (p=0.014) than REM. Therefore, MMPD provides a stronger inhibitory effect than REM at the 2.5µM concentration. 
 
 
 


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Msg # Subject Author Recs Date Posted
1201 Re: A good read if you can handle scientific lingo... billege_idiot 5 6/30/2020 3:39:10 PM






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