ZIOP-PGEN Fundamental & Technical Discussion Board - Competitors in TCR-T -- Iova, Intellia, TCRR and Timmunity - ZIOP-PGEN Fundamental & Technical Discussion Board - InvestorVillage


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Msg  25208 of 25524  at  10/28/2021 9:53:06 AM  by

dachmeister4u


 In response to msg 25207 by  dnmun
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Re: Competitors in TCR-T -- Iova, Intellia, TCRR and Timmunity


>> so since it has not already been activated, then it can be used to create the synthetic lymphocyte by gene editing, <<

Aw shucks, dnmun. I thought the metaphor that naive Tcells had not yet been programmed for their mission was a decent simplification. I'm glad you are around to square me away.

I left a question to you in #25154. Do you think that any firm has yet mastered (proven the concept in trials) in Treg control that opens the door to allogeneic from a single host and, as well, creates a market for organ transplants that do not require a close MHC match from a donor? In my view, many including Sangamo, are "working on it" but until the black boxes in CAR-T are removed, I think the challenge is not yet overcome.

Said in another way, do you know of anyone using single-host allo (approved) that does not having a black box? Thanks in advance.


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Msg # Subject Author Recs Date Posted
25213 Re: Competitors in TCR-T -- Iova, Intellia, TCRR and Timmunity dnmun 4 10/28/2021 1:08:11 PM


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