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Msg  24987 of 25210  at  9/26/2021 2:35:15 PM  by

clsm


 In response to msg 24984 by  dachmeister4u
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Re: CAR T Cells: Off the Shelf and On the Mark

FT596 has increased in vivo expansion and persistence over FT516 https://postimg.cc/bGxsP03H

CISH (a negative regulator of IL-15-mediated signaling) knockout would improve both as well as cytotoxicity https://ashpublications.org/blood/article/137/5/624/463715/Targeting-a-cytokine-checkpoint-enhances-the https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(20)30206-X


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