ZIOP-XON Fundamental & Technical Discussion Board - creating a vaccine for glioblastoma from extracellular vesicles - ZIOP-XON Fundamental & Technical Discussion Board - InvestorVillage
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Msg  13012 of 13734  at  9/17/2019 12:38:28 AM  by

dnmun

The following message was updated on 9/17/2019 12:39:45 AM.

creating a vaccine for glioblastoma from extracellular vesicles

this is more of the glioblastoma stuff, this is a technique to use extracellular vesicles as the source of the dendritic cell vaccine by removing some of immunogenic molecules from the surface so the EV could be endocytized by the dendritic cell more easily and that could lead to more of an immune response. really neat stuff to realize there is so much work against this horrible cancer. they got 25.1 months versus 14.3 months avg survival. significant imo.
 
imagine how the use of an IL-12 stimulant and the checkpoint inhibitor in combination with these techniques. 
 

Glycan modification of glioblastoma-derived extracellular vesicles enhances receptor-mediated targeting of dendritic cells

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713149/
 


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