In Caribou, Maine, following a high of 20 on Thursday, temperatures will start the day on Saturday at 28 degrees below zero. The record low is 30 below zero set in 1971. Temperatures are forecast to remain well below zero during the day on Saturday.

"At peak during the outbreak from late Friday to Saturday, AccuWeather RealFeel® Temperatures will plunge between 30 and 50 degrees below zero where many people live in central and northern New England and could plummet close to an unworldly 100 below zero on top of Mount Washington, New Hampshire," AccuWeather Senior Meteorologist Adam Douty.

People who will be spending any length of time outdoors should be prepared for the extreme cold, which can be dangerous for those with pulmonary conditions, experts warn. The risk of frostbite on exposed skin will be very high with the event from Friday night to Saturday.

Even though the harshest cold will be felt in northern New England, areas as far south as New York City and Washington, D.C., will feel the difference.

Temperatures were forecast to reach the 50s on Monday in New York City, but it will feel like the Arctic early Saturday in Manhattan with a morning low of 3 and afternoon temperatures only in the upper teens. RealFeel temperatures will dip below zero at times as the air is funneled between the concrete canyons, forecasters say. The record low temperatures in Central Park on Saturday morning is 3 set in 1918, if the wind ends up being more northerly, rather than northwesterly. A northerly wind tends to be the most efficient for funneling cold air down the Hudson Valley and right into Manhattan.

Farther south, temperatures may struggle to reach the 30-degree mark in Washington, D.C., on Saturday after starting the day off in the mid-teens.