AACE/ACE Diabetes Algorithm For Glycemic Control [Dr D's Comments -#2 added] | ARNA Message Board Posts

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Msg  56507 of 138186  at  4/24/2013 2:00:40 PM  by

jakeflies

The following message was updated on 4/24/2013 2:17:27 PM.

Re: AACE/ACE Diabetes Algorithm For Glycemic Control [Dr D's Comments -#2 added]

Re: AACE/ACE Diabetes Algorithm For Glycemic Control [Dr D's Comments -#2 added]
“The Key for Belviq is the new AACE Algorithm for all aspects of T2DM”

Obesity managment is incorporated into the new algorithm because evidence confirms that weight loss reduces blood glucose. In fact 5-10% decrease in weight can significantly improve gylcemic control as well as other weight related co-morbitidities.

ADA treatment guidelines recommend that patients with T2DM achieve modest weight loss (5-7%) to improve glycemic control – and note that weight loss is more difficult to acieive amont patients with T2DM and this was accomplished with Belviq.

Commenting on the New AACE guidlelines Dr. Garber commented that Obesity managment, in fact can be considered first-line treatment for people with prediabetes. He goes on to say that we now have medications that produce 6-12% body weight loss and that’s enough to reduce hyperglycemia and normalize the average prediabetic patient. the prediabetes algoritym addresses cardiovascular risk factor modification and offers the choice of antihyperglycemic or antiobesity therapy. The data do not yet address which is superior.

The key: Belviq is both antihyperglycemic and antiobestiy !!!

In fact, he did not mention Belivq’s ability to significantly lower A1C levels that is on par with all the hypoglycemic agents out there. Therefore it is reasonable to conclude, based on the above, that Belviq may become the first-line treatment and/or the best second-line treatment for those diagnosed with T2DM since 85% are obese.

I will expand later on Belviq and this indication

Daniel
UCLA MD

TO REITERATE:
First line treatment for prediabetes!!!
Best second-line treatment for type 2 diabetes mellitus and still possible for Belviq to be first line treatment
Decrease in A1C commensurate with the majority of hypoglycemics whether they be SFU's, GLP-1's, etc without the risks and the additional benefit of weight loss - whereas most hypoglycemics either increase weight, are weigh neutral, and the ones that do decrease weight are in the order of .14 kg above placebo.

THIS IS THE KEY TO THE SUCCESS OF BELVIQ APART FROM WEIGHT LOSS ALONE - the analysts just dont get it. Search all articles on belviq by wall street journalists and you will note a paucity of information on the diabetic benefits of Belviq!!!!

Daniel
UCLA MD

Correction:
Hypoglycemics that do decrease weight are in the order of 1.4 kg more than placebo.

Sorry about all the typos - trying to get out the info quickly because of impact the AACE algorithm has for Belviq .

Daniel
UCLA MD


 
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