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Re: PCSK9 on MDCO CallYes. We will know about it in about a year. And the dosing will be once a month or even once every two or three months depending upon the degree of KD required. In CC5 they achieved 94% KD in humans at day 70 after a single dose of 200mg which is about 2.5mg/kg. It has a very wide therapeutic index so they can even go to much higher dose if that is necessary. The point is achieving required KD is not a problem. But achieving FC is entirely a different issue. |
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Msg # | Subject | Author | Recs | Date Posted |
32248 | Re: PCSK9 on MDCO Call | tufulipo | 0 | 7/30/2015 11:33:46 PM |