Re: Coming out of hibernation, I have these other observations and questions...Patienc28e
"these submissions will be for 2nd-line mbc...te as single agent..."
"there was a 1st-line te single agent trial way back that was successful,..just hanging there..."
Not aware of one.
"the 3rd-line te single agent submission was rtc'd...probably could be re-submitted now with emilia results..."
Emilia PFS approval would include all subsequent stages of MBC treatment.
"there is the annoying 1st-line marianne trial that has pertuzumab poking its nose into the mix..."
Treatment supposedly not only effective for greater number of patients, but also for longer durations. Ask Adam to work IMGN's share of that into current $6B yearly Herceptin market.
"then there is the adjuvant trial that is on hold evaluating results..."
True, how to treat patients that had their tumors removed. Give them T-DM1 for one year to knock out all microscopic, undetectable, cancer residues or wait for cancer to recur, then go T-DM1 and/or Pertuzumab/Herceptin route?